The discussion addresses the phenomenon of "Ozempic face," where individuals using GLP-1 agonists like Ozempic, Mounjaro, and Wegovy experience weight loss accompanied by facial volume loss and sagging skin. Several solutions are presented to counteract these effects. For restoring facial volume, options include traditional hyaluronic acid fillers, newer fillers that stimulate natural fat creation, and platelet-rich plasma (PRP) derived from the patient's own blood. To address skin sagging, non-surgical devices such as radiofrequency and ultrasound are mentioned for their skin-tightening capabilities. The aim is to allow individuals to benefit from weight loss medications while maintaining a desirable facial appearance.