GLP-1 agonists, such as Ozempic and Mounjaro, facilitate weight loss but often lead to facial volume loss and skin sagging, a condition termed "Ozempic face." Several aesthetic treatments can address these concerns. To restore facial volume, options include traditional hyaluronic acid fillers, newer fillers designed to stimulate natural fat production, and platelet-rich plasma (PRP) derived from the patient's own blood. For skin tightening and addressing sagging, non-surgical devices like radiofrequency and ultrasound technologies are available. These interventions allow individuals to achieve weight loss while mitigating unwanted facial changes, enhancing overall appearance.